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Cellosaurus GM10855 (CVCL_R610)

[Text version]
Cell line name GM10855
Accession CVCL_R610
Resource Identification Initiative To cite this cell line use: GM10855 (RRID:CVCL_R610)
Comments Part of: CEPH/Utah pedigree cell line collection.
Part of: International Genome Sample Resource (1000 genomes project) cell lines.
Registration: CEPH Families Reference Panel; 135002.
Population: Caucasian; Utah residents with ancestry from Northern and Western Europe.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: CNV analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 2623; CYP2C9; Simple; p.Ile359Leu (c.1075A>C); ClinVar=VCV000008408; Zygosity=Heterozygous; Note=CYP2C9*3 allele (Coriell=GM10855).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Web pages https://www.cephb.fr/en/familles_CEPH.php
Publications

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=15514893; DOI=10.1086/426461
Monks S.A., Leonardson A., Zhu H., Cundiff P., Pietrusiak P., Edwards S., Phillips J.W., Sachs A., Schadt E.E.
Genetic inheritance of gene expression in human cell lines.
Am. J. Hum. Genet. 75:1094-1105(2004)

PubMed=17122850; DOI=10.1038/nature05329
Redon R., Ishikawa S., Fitch K.R., Feuk L., Perry G.H., Andrews T.D., Fiegler H., Shapero M.H., Carson A.R., Chen W.-W., Cho E.K., Dallaire S., Freeman J.L., Gonzalez J.R., Gratacos M., Huang J., Kalaitzopoulos D., Komura D., MacDonald J.R., Marshall C.R., Mei R., Montgomery L., Nishimura K., Okamura K., Shen F., Somerville M.J., Tchinda J., Valsesia A., Woodwark C., Yang F.-T., Zhang J.-J., Zerjal T., Zhang J., Armengol L., Conrad D.F., Estivill X., Tyler-Smith C., Carter N.P., Aburatani H., Lee C., Jones K.W., Scherer S.W., Hurles M.E.
Global variation in copy number in the human genome.
Nature 444:444-454(2006)

PubMed=19043577; DOI=10.1371/journal.pgen.1000287
Choy E., Yelensky R., Bonakdar S., Plenge R.M., Saxena R., De Jager P.L., Shaw S.Y., Wolfish C.S., Slavik J.M., Cotsapas C., Rivas M.A., Dermitzakis E.T., Cahir-McFarland E., Kieff E.D., Hafler D.A., Daly M.J., Altshuler D.M.
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.
PLoS Genet. 4:E1000287-E1000287(2008)

PubMed=20856902; DOI=10.1371/journal.pbio.1000480
Cheung V.G., Nayak R.R., Wang I.X.-R., Elwyn S., Cousins S.M., Morley M., Spielman R.S.
Polymorphic cis- and trans-regulation of human gene expression.
PLoS Biol. 8:e1000480.1-e1000480.14(2010)

PubMed=21397061; DOI=10.1016/j.ajhg.2011.02.004
Campbell C.D., Sampas N., Tsalenko A., Sudmant P.H., Kidd J.M., Malig M., Vu T.H., Vives L., Tsang P., Bruhn L., Eichler E.E.
Population-genetic properties of differentiated human copy-number polymorphisms.
Am. J. Hum. Genet. 88:317-332(2011)

PubMed=24924344; DOI=10.1186/1756-0500-7-360
Hariani G.D., Lam E.J., Havener T., Kwok P.-Y., McLeod H.L., Wagner M.J., Motsinger-Reif A.A.
Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics.
BMC Res. Notes 7:360.1-360.10(2014)

PubMed=26621101; DOI=10.1016/j.jmoldx.2015.08.005
Pratt V.M., Everts R.E., Aggarwal P., Beyer B.N., Broeckel U., Epstein-Baak R., Hujsak P., Kornreich R., Liao J., Lorier R., Scott S.A., Smith C.-Y.H., Toji L.H., Turner A., Kalman L.V.
Characterization of 137 genomic DNA reference materials for 28 pharmacogenetic genes: a GeT-RM collaborative project.
J. Mol. Diagn. 18:109-123(2016)

PubMed=31401124; DOI=10.1016/j.jmoldx.2019.06.007
Gaedigk A., Turner A., Everts R.E., Scott S.A., Aggarwal P., Broeckel U., McMillin G.A., Melis R., Boone E.C., Pratt V.M., Kalman L.V.
Characterization of reference materials for genetic testing of CYP2D6 alleles: a GeT-RM collaborative project.
J. Mol. Diagn. 21:1034-1052(2019)

PubMed=35931342; DOI=10.1016/j.jmoldx.2022.06.008
Pratt V.M., Wang W.Y., Boone E.C., Broeckel U., Cody N., Edelmann L.J., Gaedigk A., Lynnes T.C., Medeiros E., Moyer A.M., Mitchell M.M., Scott S.A., Starostik P., Turner A., Kalman L.V.
Characterization of reference materials for TPMT and NUDT15: a GeT-RM collaborative project.
J. Mol. Diagn. 24:1079-1088(2022)

Cross-references
Cell line collections (Providers) Coriell; GM10855
Cell line databases/resources CLO; CLO_0023763
Biological sample resources BioSample; SAMN00800274
IGSR; NA10855
Encyclopedic resources Wikidata; Q54844688
Gene expression databases GEO; GSM30054
GEO; GSM112503
GEO; GSM112783
GEO; GSM291614
GEO; GSM420632
GEO; GSM648870
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number25