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Cellosaurus 4T1-mNIS (monoclonal) (CVCL_QZ61)

[Text version]
Cell line name 4T1-mNIS (monoclonal)
Accession CVCL_QZ61
Resource Identification Initiative To cite this cell line use: 4T1-mNIS (monoclonal) (RRID:CVCL_QZ61)
Comments Characteristics: Transfected with the LV-mNIS vector encoding mouse Slc5a5 under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL117).
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Genetic integration: Method=Transfection; Gene=MGI; MGI:2149330; Slc5a5.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cfC3H.
Hierarchy Parent: CVCL_0125 (4T1)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=30674994; DOI=10.1038/s41417-019-0081-2; PMCID=PMC7170803
Vandergaast R., Khongwichit S., Jiang H.-L., DeGrado T.R., Peng K.-W., Smith D.R., Russell S.J., Suksanpaisan L.
Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging.
Cancer Gene Ther. 27:179-188(2020)

Cross-references
Cell line collections (Providers) Imanis; CL117
Encyclopedic resources Wikidata; Q54603544
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number8