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Cellosaurus HuCC-T1-G100 (CVCL_QZ45)

[Text version]
Cell line name HuCC-T1-G100
Synonyms HuCCT1-G100
Accession CVCL_QZ45
Resource Identification Initiative To cite this cell line use: HuCC-T1-G100 (RRID:CVCL_QZ45)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Lys1358fs*2 (c.4071_4072insGATT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0324 (HuCC-T1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=21451941; DOI=10.1007/s00534-011-0376-7
Sato J., Kimura T., Saito T., Anazawa T., Kenjo A., Sato Y., Tsuchiya T., Gotoh M.
Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma.
J. Hepatobiliary Pancreat. Sci. 18:700-711(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_QZ45
Encyclopedic resources Wikidata; Q54896727
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number10