Cellosaurus cell line LEF1 (CVCL

Cellosaurus LEF1 (CVCL_QW98)

Cross-references
Cell line name	LEF1
Synonyms	LEF-1
Accession	CVCL_QW98
Resource Identification Initiative	To cite this cell line use: LEF1 (RRID:CVCL_QW98)
Comments	Karyotypic information: 46,XX,t(9;22)(q34;q11) (PubMed=2143794). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=2143794; PubMed=10071072).
Disease	Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819) B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	37Y
Category	Cancer cell line
Publications	PubMed=2143794 Grausz D., Lanotte M., Valensi F., Hillion J., Chen S.-J., Chen Z., Morinet F., Berger R. A new Ph1+, bcr cell line derived from a patient with ALL-L1 gained autonomy in culture concomitant to CD23 expression. Leukemia 4:359-364(1990) PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4 Drexler H.G., MacLeod R.A.F., Uphoff C.C. Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res. 23:207-215(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)
Encyclopedic resources	Wikidata; Q54902435
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	11