Cellosaurus cell line HS-ES-2M BAF47 (CVCL

Cellosaurus HS-ES-2M BAF47 (CVCL_QW56)

Cross-references
Cell line name	HS-ES-2M BAF47
Synonyms	HS-ES-2M_BAF47; HSES2M_BAF47
Accession	CVCL_QW56
Resource Identification Initiative	To cite this cell line use: HS-ES-2M BAF47 (RRID:CVCL_QW56)
Comments	Population: Japanese. Characteristics: Transfection of SMARCB1 rescues the phenotype of the parent cell line which is heterozygous for its deletion. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11103; SMARCB1. Omics: Genomics; ChIP-seq; H3K27ac. Omics: Genomics; ChIP-seq; H3K27me3. Omics: Genomics; ChIP-seq; H3K4me3. Omics: Transcriptomics; RNAseq. Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease	Epithelioid sarcoma (NCIt: C3714) Epithelioid sarcoma (ORDO: Orphanet_293202)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_8714 (HS-ES-2M)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080 Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C. SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters. Nat. Genet. 49:1613-1623(2017)
Encyclopedic resources	Wikidata; Q54896282
Gene expression databases	GEO; GSM2409688 GEO; GSM2409689 GEO; GSM2409690 GEO; GSM2409691 GEO; GSM2409692 GEO; GSM2409693 GEO; GSM2787357
Entry history
Entry creation	15-Nov-2017
Last entry update	10-Apr-2025
Version number	10