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Cellosaurus HS-ES-2M BAF47 (CVCL_QW56)

[Text version]
Cell line name HS-ES-2M BAF47
Synonyms HS-ES-2M_BAF47; HSES2M_BAF47
Accession CVCL_QW56
Resource Identification Initiative To cite this cell line use: HS-ES-2M BAF47 (RRID:CVCL_QW56)
Comments Population: Japanese.
Characteristics: Transfection of SMARCB1 rescues the phenotype of the parent cell line which is heterozygous for its deletion.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11103; SMARCB1.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Epithelioid sarcoma (NCIt: C3714)
Epithelioid sarcoma (ORDO: Orphanet_293202)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8714 (HS-ES-2M)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080
Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Cross-references
Encyclopedic resources Wikidata; Q54896282
Gene expression databases GEO; GSM2409688
GEO; GSM2409689
GEO; GSM2409690
GEO; GSM2409691
GEO; GSM2409692
GEO; GSM2409693
GEO; GSM2787357
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9