Cellosaurus logo
expasy logo

Cellosaurus HEK293T SMARCB1-/- (CVCL_QW54)

[Text version]
Cell line name HEK293T SMARCB1-/-
Synonyms SMARCB1-/- HEK293T; BAF47-knockout HEK293T
Accession CVCL_QW54
Resource Identification Initiative To cite this cell line use: HEK293T SMARCB1-/- (RRID:CVCL_QW54)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11103; SMARCB1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080
Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Cross-references
Encyclopedic resources Wikidata; Q54882490
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9