ID   CL97
AC   CVCL_N826
SY   CL97TM/GA
DR   cancercelllines; CVCL_N826
DR   ChEMBL-Cells; CHEMBL4513104
DR   ChEMBL-Targets; CHEMBL4513122
DR   Cosmic; 1790396
DR   PRIDE; PXD001548
DR   PRIDE; PXD002224
DR   PubChem_Cell_line; CVCL_N826
DR   Wikidata; Q54813529
RX   PubMed=23024022;
RX   PubMed=26202522;
RX   PubMed=26554430;
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Gly719Ala (c.2156G>C); ClinVar=VCV000045225; Zygosity=Unspecified (PubMed=23024022).
CC   Sequence variation: Mutation; HGNC; 3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Unspecified (PubMed=23024022).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=23024022; PubMed=26202522).
CC   Omics: Deep membrane proteome analysis.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 18
//
RX   PubMed=23024022; DOI=10.1164/rccm.201207-1180OC;
RA   Yeh C.-T., Wu A.T.H., Chang P.M.-H., Chen K.-Y., Yang C.-N.,
RA   Yang S.-C., Ho C.-C., Chen C.-C., Kuo Y.-L., Lee P.-Y., Liu Y.-W.,
RA   Yen C.-C., Hsiao M., Lu P.-J., Lai J.-M., Wang L.-S., Wu C.-H.,
RA   Chiou J.-F., Yang P.-C., Huang C.-Y.F.;
RT   "Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell
RT   growth and overcomes drug resistance of lung cancer.";
RL   Am. J. Respir. Crit. Care Med. 186:1180-1188(2012).
//
RX   PubMed=26202522; DOI=10.1021/acs.jproteome.5b00477; PMCID=PMC4761227;
RA   Kitata R.B., Dimayacyac-Esleta B.R.T., Choong W.-K., Tsai C.-F.,
RA   Lin T.-D., Tsou C.-C., Weng S.-H., Chen Y.-J., Yang P.-C., Arco S.D.,
RA   Nesvizhskii A.I., Sung T.-Y., Chen Y.-J.;
RT   "Mining missing membrane proteins by high-pH reverse-phase stagetip
RT   fractionation and multiple reaction monitoring mass spectrometry.";
RL   J. Proteome Res. 14:3658-3669(2015).
//
RX   PubMed=26554430; DOI=10.1021/acs.analchem.5b03639;
RA   Dimayacyac-Esleta B.R.T., Tsai C.-F., Kitata R.B., Lin P.-Y., Choong W.-K.,
RA   Lin T.-D., Wang Y.-T., Weng S.-H., Yang P.-C., Arco S.D., Sung T.-Y.,
RA   Chen Y.-J.;
RT   "Rapid high-pH reverse phase stagetip for sensitive small-scale
RT   membrane proteomic profiling.";
RL   Anal. Chem. 87:12016-12023(2015).
//