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Cellosaurus 41M-cisR (CVCL_N788)

[Text version]
Cell line name 41M-cisR
Synonyms 41M/cisR; 41McisR
Accession CVCL_N788
Resource Identification Initiative To cite this cell line use: 41M-cisR (RRID:CVCL_N788)
Comments Problematic cell line: Contaminated. Parent cell line (41M) has been shown to be a OAW28 derivative.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Omics: Transcriptome analysis by microarray.
Misspelling: M41CisR; GEO=GSM851923.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4993 (41M)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO11
D2S133820,23
D3S135814,18
D5S81812
D7S82011
D8S117911,15
D13S31711
D16S53913
D18S5112,14
D19S43313
D21S1129
FGA21,24
TH019
TPOX8
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=1617660
Kelland L.R., Mistry P., Abel G., Loh S.Y., O'Neill C.F., Murrer B.A., Harrap K.R.
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
Cancer Res. 52:3857-3864(1992)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_N788
Chemistry resources ChEMBL-Cells; CHEMBL3989321
PubChem_Cell_line; CVCL_N788
Encyclopedic resources Wikidata; Q54602997
Gene expression databases GEO; GSM851923
Polymorphism and mutation databases Cosmic; 1609533
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number22