ID   NCE-G 112
AC   CVCL_N740
SY   NCE G-112; NCE G 112; NCE-G112; G-112; G112; NeuroChirurgie Eppendorf-Glioma 112
DR   EFO; EFO_0006396
DR   ArrayExpress; E-MTAB-2706
DR   BioSample; SAMN03471511
DR   cancercelllines; CVCL_N740
DR   EGA; EGAS00001000610
DR   IARC_TP53; 2144
DR   IARC_TP53; 21609
DR   PharmacoDB; G112_378_2019
DR   Wikidata; Q54907651
RX   DOI=10.1007/0-306-46861-1_11;
RX   PubMed=8154317;
RX   PubMed=8253536;
RX   PubMed=8289093;
RX   PubMed=10630978;
RX   PubMed=15816541;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26589293;
CC   HLA typing: A*01:01,01:01; B*08:01,08:01; C*07:01,07:01 (PubMed=26589293).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (PubMed=8253536; PubMed=15816541).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.
ST   Source(s): PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 12
ST   D21S11: 28
ST   D3S1358: 14,17
ST   D5S818: 11
ST   D7S820: 9,10
ST   D8S1179: 13,15
ST   FGA: 22
ST   Penta D: 9,12
ST   Penta E: 7,11
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 23
//
RX   DOI=10.1007/0-306-46861-1_11;
RA   Ali-Osman F.;
RT   "Brain tumors.";
RL   (In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999).
//
RX   PubMed=8154317; DOI=10.1007/BF01476489;
RA   Westphal M., Hansel M., Hamel W., Kunzmann R., Holzel F.;
RT   "Karyotype analyses of 20 human glioma cell lines.";
RL   Acta Neurochir. (Wien) 126:17-26(1994).
//
RX   PubMed=8253536; DOI=10.1002/ijc.2910550618;
RA   Anker L., Ohgaki H., Ludeke B.I., Herrmann H.-D., Kleihues P.,
RA   Westphal M.;
RT   "p53 protein accumulation and gene mutations in human glioma cell
RT   lines.";
RL   Int. J. Cancer 55:982-987(1993).
//
RX   PubMed=8289093; DOI=10.1007/BF01324703;
RA   Hamel W., Westphal M., Shepard H.M.;
RT   "Loss in expression of the retinoblastoma gene product in human
RT   gliomas is associated with advanced disease.";
RL   J. Neurooncol. 16:159-165(1993).
//
RX   PubMed=10630978; DOI=10.1667/0033-7587(2000)153[0062:FORIMI]2.0.CO;2;
RA   Akudugu J.M., Slabbert J.P., Serafin A.M., Bohm L.;
RT   "Frequency of radiation-induced micronuclei in neuronal cells does not
RT   correlate with clonogenic survival.";
RL   Radiat. Res. 153:62-67(2000).
//
RX   PubMed=15816541;
RA   Kim E.L., Yoshizato K., Kluwe L., Meissner H., Warnecke G., Zapf S.,
RA   Westphal M., Deppert W., Giese A.;
RT   "Comparative assessment of the functional p53 status in glioma
RT   cells.";
RL   Anticancer Res. 25:213-224(2005).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S.,
RA   Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G.,
RA   Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J.,
RA   Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L.,
RA   Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J.,
RA   Settleman J., Seshagiri S., Zhang Z.-M.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//