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Cellosaurus NCE-G 84 (CVCL_N735)

[Text version]
Cell line name NCE-G 84
Synonyms NCE G 84; NCE-G84; G-84; G84; NeuroChirurgie Eppendorf-Glioma 84
Accession CVCL_N735
Resource Identification Initiative To cite this cell line use: NCE-G 84 (RRID:CVCL_N735)
Comments Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala79Val (c.236C>T); Zygosity=Unspecified (PubMed=15816541).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*03:01,30:01
HLA-BB*08:01,51:01
HLA-CC*07:01,15:02
Disease Anaplastic astrocytoma (NCIt: C9477)
Anaplastic astrocytoma (ORDO: Orphanet_251589)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO11,13
D3S135816
D5S81811,13
D7S82012
D8S117913,14
D13S31712
D16S53911
D18S5119
D21S1129
FGA21
Penta D12,13
Penta E12
TH019.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8289093; DOI=10.1007/BF01324703
Hamel W., Westphal M., Shepard H.M.
Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease.
J. Neurooncol. 16:159-165(1993)

PubMed=16696057; DOI=10.1136/mp.49.2.M91; PMCID=PMC408028
Li W.-X., Martinerie C., Zumkeller W., Westphal M., Perbal B.
Differential expression of novH and CTGF in human glioma cell lines.
Clin. Mol. Pathol. 49:M91-M97(1996)

PubMed=15816541
Kim E.L., Yoshizato K., Kluwe L., Meissner H., Warnecke G., Zapf S., Westphal M., Deppert W., Giese A.
Comparative assessment of the functional p53 status in glioma cells.
Anticancer Res. 25:213-224(2005)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

Cross-references
Biological sample resources BioSample; SAMN03471545
Chemistry resources PharmacoDB; G84_393_2019
Encyclopedic resources Wikidata; Q54907690
Experimental variables resources EFO; EFO_0006411
Gene expression databases ArrayExpress; E-MTAB-2706
Polymorphism and mutation databases IARC_TP53; 21612
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number18