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Cellosaurus 1273/99 (CVCL_N588)

[Text version]
Cell line name 1273/99
Synonyms 1273-99; 127399; 1273
Accession CVCL_N588
Resource Identification Initiative To cite this cell line use: 1273/99 (RRID:CVCL_N588)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Sequence variations
  • Gene fusion; HGNC; 11340; SS18 + HGNC; 11336; SSX2; Name(s)=SS18-SSX2 (PubMed=12097301; DepMap).
Disease Synovial sarcoma (NCIt: C3400)
Synovial sarcoma (ORDO: Orphanet_3273)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=12097301
Xie Y.-T., Skytting B., Nilsson G., Gasbarri A., Haslam K., Bartolazzi A., Brodin B., Mandahl N., Larsson O.
SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: a gain of function of the t(X;18)(p11.2;q11.2) translocation.
Cancer Res. 62:3861-3867(2002)

PubMed=24726063; DOI=10.1186/1756-9966-33-33
Koelsche C., Renner M., Hartmann W., Brandt R., Lehner B., Waldburger N., Alldinger I., Schmitt T., Egerer G., Penzel R., Wardelmann E., Schirmacher P., von Deimling A., Mechtersheimer G.
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_N588
Cell_Model_Passport; SIDM01315
DepMap; ACH-001270
Encyclopedic resources Wikidata; Q54581310
Polymorphism and mutation databases Cosmic; 2307723
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number15