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Cellosaurus CME-1 (CVCL_N586)

[Text version]
Cell line name CME-1
Synonyms CME1; CME
Accession CVCL_N586
Resource Identification Initiative To cite this cell line use: CME-1 (RRID:CVCL_N586)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Deep exome analysis.
Sequence variations
  • Gene fusion; HGNC; 11340; SS18 + HGNC; 11336; SSX2; Name(s)=SS18-SSX2 (PubMed=7736791; DepMap).
Disease Monophasic synovial sarcoma (NCIt: C6534)
Synovial sarcoma (ORDO: Orphanet_3273)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Transformed cell line
Publications

PubMed=7736791; DOI=10.1159/000133992
Renwick P.J., Reeves B.R., Dal Cin P.S., Fletcher C.D.M., Kempski H., Sciot R., Kazmierczak B., Jani K., Sonobe H., Knight J.C.
Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma.
Cytogenet. Cell Genet. 70:58-63(1995)

PubMed=24726063; DOI=10.1186/1756-9966-33-33
Koelsche C., Renner M., Hartmann W., Brandt R., Lehner B., Waldburger N., Alldinger I., Schmitt T., Egerer G., Penzel R., Wardelmann E., Schirmacher P., von Deimling A., Mechtersheimer G.
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01489
DepMap; ACH-001322
Anatomy/cell type resources BTO; BTO:0006385
Encyclopedic resources Wikidata; Q54813754
Polymorphism and mutation databases Cosmic; 2307727
Entry history
Entry creation05-Nov-2013
Last entry update21-Mar-2023
Version number14