Cellosaurus cell line CME-1 (CVCL

Cellosaurus CME-1 (CVCL_N586)

Cross-references
Cell line name	CME-1
Synonyms	CME1; CME
Accession	CVCL_N586
Resource Identification Initiative	To cite this cell line use: CME-1 (RRID:CVCL_N586)
Comments	Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Omics: Deep exome analysis.
Sequence variations	Gene fusion; HGNC; HGNC:11340; SS18 + HGNC; HGNC:11336; SSX2; Name(s)=SS18-SSX2 (PubMed=7736791; DepMap=ACH-001322).
Disease	Monophasic synovial sarcoma (NCIt: C6534) Synovial sarcoma (ORDO: Orphanet_3273)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Category	Transformed cell line
Publications	PubMed=7736791; DOI=10.1159/000133992 Renwick P.J., Reeves B.R., Dal Cin P.S., Fletcher C.D.M., Kempski H.M., Sciot R., Kazmierczak B., Jani K., Sonobe H., Knight J.C. Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma. Cytogenet. Cell Genet. 70:58-63(1995) PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359 Koelsche C., Renner M., Hartmann W., Brandt R., Lehner B., Waldburger N., Alldinger I., Schmitt T., Egerer G., Penzel R., Wardelmann E., Schirmacher P., von Deimling A., Mechtersheimer G. TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities. J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)
Cell line databases/resources	Cell_Model_Passport; SIDM01489 DepMap; ACH-001322
Anatomy/cell type resources	BTO; BTO_0006385
Encyclopedic resources	Wikidata; Q54813754
Polymorphism and mutation databases	Cosmic; 2307727
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	16