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Cellosaurus GM09948 (CVCL_N127)

[Text version]
Cell line name GM09948
Synonyms GM9948; 9948; GM09948A; GM17235
Accession CVCL_N127
Resource Identification Initiative To cite this cell line use: GM09948 (RRID:CVCL_N127)
Comments Part of: Genetic Testing Reference Material (GeT-RM) samples.
Part of: Human variation panel.
Registration: National Institute of Standards and Technology, Standard Reference Materials; SRM 2391b.
Population: Caucasian.
Biotechnology: Used a source of control genomic DNA for USA forensic testing.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: DNA methylation analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
HLA typing Source: PubMed=29959025
Class I
HLA-AA*03:01:01,31:01:02
HLA-BB*07:02:01,40:01:02
HLA-CC*03:04:01,07:02:01
Class II
HLA-DPDPA1*01:03:01,01:03:01
DPB1*04:01:01,04:01:01
HLA-DQDQA1*01:02:01,03:01:01
DQB1*03:02:01,06:02:01
HLA-DRDRB1*04:04:01,15:01:01
DRB4*01:03:01
DRB5*01:01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 31Y
Category Transformed cell line
STR profile Source(s): CelloPub=CLPUB00756; CelloPub=CLPUB00757; PubMed=14642717; PubMed=24266330

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D1S165614,17
D2S44111,12
D2S133823
D3S135815,17
D5S81811,13
D7S82011
D8S117912,13
D10S124812,15
D12S39118,24
D13S31711
D16S53911
D18S5115,18
D19S43313,14
D21S1129,30
D22S104516,18
DXS10125
DYS39110
F13A016
F13B8
FESFPS11
FGA24,26
LPL10,12
Penta D8,12
Penta E11
SE3323.2,26.2
TH016,9.3
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=8530025; DOI=10.1006/geno.1995.1130
Fregeau C.J., Aubin R.A., Elliott J.C., Gill S.S., Fourney R.M.
Characterization of human lymphoid cell lines GM9947 and GM9948 as intra- and interlaboratory reference standards for DNA typing.
Genomics 28:184-197(1995)

PubMed=14642717; DOI=10.1016/j.forsciint.2003.09.002
Szibor R., Edelmann J., Hering S., Plate I., Wittig H., Roewer L., Wiegand P., Cali F., Romano V., Michael M.
Cell line DNA typing in forensic genetics -- the necessity of reliable standards.
Forensic Sci. Int. 138:37-43(2003)

PubMed=14583597; DOI=10.1152/physiolgenomics.00163.2003
Pastinen T., Sladek R., Gurd S., Sammak A., Ge B., Lepage P., Lavergne K., Villeneuve A., Gaudin T., Brandstrom H., Beck A., Verner A., Kingsley J., Harmsen E., Labuda D., Morgan K., Vohl M.-C., Naumova A.K., Sinnett D., Hudson T.J.
A survey of genetic and epigenetic variation affecting human gene expression.
Physiol. Genomics 16:184-193(2004)

PubMed=16260726; DOI=10.1073/pnas.0508390102
Harris S.L., Gil G., Robins H., Hu W.-W., Hirshfield K.M., Bond E., Bond G., Levine A.J.
Detection of functional single-nucleotide polymorphisms that affect apoptosis.
Proc. Natl. Acad. Sci. U.S.A. 102:16297-16302(2005)

CLPUB00756
National Institute of Standards and Technology
Certificate of analysis: Standard Reference Material 2391b.
(In) NIST SRM 2391b; pp.1-8; NIST; Gaithersburg (2008)

PubMed=20889555; DOI=10.2353/jmoldx.2010.100090
Pratt V.M., Zehnbauer B.A., Wilson J.A., Epstein-Baak R., Babic N., Bettinotti M.P., Buller-Burckle A.M., Butz K.G., Campbell M., Civalier C., El-Badry A., Farkas D.H., Lyon E., Mandal S., McKinney J., Muralidharan K., Noll L., Sander T., Shabbeer J., Smith C.-Y.H., Telatar M., Toji L.H., Vairavan A., Vance C., Weck K.E., Wu A.H.B., Yeo K.-T.J., Zeller M., Kalman L.V.
Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project.
J. Mol. Diagn. 12:835-846(2010)

PubMed=24266330; DOI=10.1021/ac403137h
Geng T., Novak R., Mathies R.A.
Single-cell forensic short tandem repeat typing within microfluidic droplets.
Anal. Chem. 86:703-712(2014)

CLPUB00757
Promega Corporation
PowerPlex Fusion 6C system. Instructions for use of products DC2705 and DC2720.
(In) Promega Technical manual TMD045; pp.1-75; Promega Corp.; Madison (2015)

PubMed=26621101; DOI=10.1016/j.jmoldx.2015.08.005
Pratt V.M., Everts R.E., Aggarwal P., Beyer B.N., Broeckel U., Epstein-Baak R., Hujsak P., Kornreich R., Liao J., Lorier R., Scott S.A., Smith C.-Y.H., Toji L.H., Turner A., Kalman L.V.
Characterization of 137 genomic DNA reference materials for 28 pharmacogenetic genes: a GeT-RM collaborative project.
J. Mol. Diagn. 18:109-123(2016)

PubMed=29959025; DOI=10.1016/j.jmoldx.2018.05.009
Bettinotti M.P., Ferriola D., Duke J.L., Mosbruger T.L., Tairis N., Jennings L., Kalman L.V., Monos D.S.
Characterization of 108 genomic DNA reference materials for 11 human leukocyte antigen loci: a GeT-RM collaborative project.
J. Mol. Diagn. 20:703-715(2018)

Cross-references
Cell line collections (Providers) Coriell; GM09948
Coriell; GM17235
Cell line databases/resources CLO; CLO_0014334
CLO; CLO_0029744
Encyclopedic resources Wikidata; Q54844134
Gene expression databases GEO; GSM569605
GEO; GSM596299
GEO; GSM596659
GEO; GSM924837
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number22