Cellosaurus cell line TSU-Pr1-B2 (CVCL

Cross-references
Cell line name	TSU-Pr1-B2
Accession	CVCL_M905
Resource Identification Initiative	To cite this cell line use: TSU-Pr1-B2 (RRID:CVCL_M905)
Comments	Problematic cell line: Contaminated. Grand-parent cell line (TSU-Pr1) has been shown to be a T24 derivative. Population: Caucasian; Swedish. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations	Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease	Bladder carcinoma (NCIt: C4912)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_M904 (TSU-Pr1-B1)
Sex of cell	Female
Age at sampling	82Y
Category	Cancer cell line
Publications	PubMed=16086232; DOI=10.1007/s10585-005-5141-3 Chaffer C.L., Dopheide B., McCulloch D.R., Lee A.B., Moseley J.M., Thompson E.W., Williams E.D. Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder. Clin. Exp. Metastasis 22:115-125(2005)
Cell line databases/resources	cancercelllines; CVCL_M905
Encyclopedic resources	Wikidata; Q54973172
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	17