Cell line name |
T24T |
Accession |
CVCL_M892 |
Resource Identification Initiative |
To cite this cell line use: T24T (RRID:CVCL_M892) |
Comments |
Population: Caucasian; Swedish. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
Sequence variations |
- Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
|
Disease |
Bladder carcinoma (NCIt: C4912) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0554 (T24) Children:
|
Sex of cell |
Female |
Age at sampling |
82Y |
Category |
Cancer cell line |
Publications | PubMed=10679914; DOI=10.1002/(SICI)1098-2264(200003)27:3<252::AID-GCC5>3.0.CO;2-9 Gildea J.J., Golden W.L., Harding M.A., Theodorescu D. Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer. Genes Chromosomes Cancer 27:252-263(2000) PubMed=12460916 Harding M.A., Arden K.C., Gildea J.W., Gildea J.J., Perlman E.J., Viars C., Theodorescu D. Functional genomic comparison of lineage-related human bladder cancer cell lines with differing tumorigenic and metastatic potentials by spectral karyotyping, comparative genomic hybridization, and a novel method of positional expression profiling. Cancer Res. 62:6981-6989(2002) PubMed=15520187; DOI=10.1158/0008-5472.CAN-04-0826 Nicholson B.E., Frierson H.F. Jr., Conaway M.R., Seraj J.M., Harding M.A., Hampton G.M., Theodorescu D. Profiling the evolution of human metastatic bladder cancer. Cancer Res. 64:7813-7821(2004) PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D. Systematic review: characteristics and preclinical uses of bladder cancer cell lines. Bladder Cancer 4:169-183(2018) |
Cross-references |
Cell line collections (Providers) |
Millipore; SCC468
|
Cell line databases/resources |
cancercelllines; CVCL_M892
|
Encyclopedic resources |
Wikidata; Q54971468
|
Entry history |
Entry creation | 05-Nov-2013 |
Last entry update | 19-Dec-2024 |
Version number | 16 |
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