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Cellosaurus BFTC-905-diffuse (CVCL_M889)

[Text version]
Cell line name BFTC-905-diffuse
Accession CVCL_M889
Resource Identification Initiative To cite this cell line use: BFTC-905-diffuse (RRID:CVCL_M889)
Comments Population: Chinese; Taiwan.
Characteristics: Differs from the BFTC-905-compact cell line by growing in a less organized, 'diffuse' manner, which involves colonies of cells exhibiting apparently normal cell-to-cell adhesion as well as individual cells outside of them (PubMed=18398596).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.673-2A>T (IVS6-2A>T); ClinVar=VCV000635388; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1083 (BFTC-905)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=18398596; DOI=10.1007/s00120-008-1687-4
Hatina J., Huckenbeck W., Rieder H., Seifert H.-H., Schulz W.A.
Bladder carcinoma cell lines as models of the pathobiology of bladder cancer. Review of the literature and establishment of a new progression series.
Urologe A 47:724-734(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M889
Encyclopedic resources Wikidata; Q54796205
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number16