ID   T-1
AC   CVCL_M858
SY   T1
DR   BioSample; SAMN03151761
DR   Wikidata; Q54971324
RX   CelloPub=CLPUB00262;
RX   DOI=10.2172/4683311;
RX   PubMed=1167420;
RX   PubMed=4288260;
RX   PubMed=5660764;
RX   PubMed=7394535;
RX   PubMed=13545791;
RX   PubMed=13686930;
RX   PubMed=20143388;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=7394535; PubMed=20143388). Originally thought to originate from the kidney of a 8 year old boy.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00095.
CC   Population: African American.
CC   Doubling time: ~22-24 hours (DOI=10.2172/4683311).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 30-01-24; Version: 19
RX   CelloPub=CLPUB00262;
RA   Gold M.;
RT   "A conspiracy of cells. One woman's immortal legacy and the medical
RT   scandal it caused.";
RL   (In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986).
RX   DOI=10.2172/4683311;
RA   Todd P.W.;
RT   "Reversible and irreversible effects of ionizing radiations on the
RT   reproductive integrity of mammalian cells cultured in vitro.";
RL   Thesis PhD (1964), University of California, United States.
RX   PubMed=1167420; DOI=10.2307/3574046;
RA   Todd P.W.;
RT   "Heavy-ion irradiation of human and Chinese hamster cells in vitro.";
RL   Radiat. Res. 61:288-297(1975).
RX   PubMed=4288260; DOI=10.1007/BF02097456;
RA   Peutz-de Jong M., Mes A., van der Veen J.;
RT   "Susceptibility of cell lines of primate and nonprimate origin to
RT   certain human viruses.";
RL   Antonie Van Leeuwenhoek 32:162-169(1966).
RX   PubMed=5660764; DOI=10.1016/0027-5107(68)90090-0;
RA   Todd P.W.;
RT   "Defective mammalian cells isolated from X-irradiated cultures.";
RL   Mutat. Res. 5:173-183(1968).
RX   PubMed=7394535; DOI=10.1126/science.7394535;
RA   Nelson-Rees W.A., Flandermeyer R.R., Daniels D.W.;
RT   "T-1 cells are HeLa and not of normal human kidney origin.";
RL   Science 209:719-720(1980).
RX   PubMed=13545791; DOI=10.1007/BF01241484;
RA   van der Veen J., Bots L., Mes A.;
RT   "Establishment of two human cell strains from kidney and
RT   reticulosarcoma in lung.";
RL   Arch. Gesamte Virusforsch. 8:230-238(1958).
RX   PubMed=13686930; DOI=10.2307/3570859;
RA   Barendsen G.W., Beusker T.L., Vergroesen A.J., Budke L.;
RT   "Effects of different radiations on human cells in tissue culture. II.
RT   Biological experiments.";
RL   Radiat. Res. 13:841-849(1960).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).