ID   NOS-1 [Human HNSCC]
AC   CVCL_M837
DR   cancercelllines; CVCL_M837
DR   IARC_TP53; 17855
DR   Wikidata; Q54930910
RX   PubMed=11291288;
RX   PubMed=11337272;
CC   Population: Japanese.
CC   Doubling time: 16.1 hours (Note=At 100th passage) (PubMed=11291288; PubMed=11337272).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (PubMed=11337272).
CC   Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
DI   NCIt; C8171; Lower gingival squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 16
//
RX   PubMed=11291288;
RA   Ji Z.-W., Oku N., Komori T.;
RT   "Establishment of a novel human squamous cell carcinoma cell line from
RT   oral primary tumor by geneticin treatment.";
RL   Kobe J. Med. Sci. 46:137-145(2000).
//
RX   PubMed=11337272; DOI=10.1016/S1368-8375(00)00088-9;
RA   Ji Z.-W., Oku N., Umeda M., Komori T.;
RT   "Establishment of an oral squamous cell carcinoma cell line (NOS-1)
RT   exhibiting amplification of the erbB-1 oncogene and point mutation of
RT   p53 tumor suppressor gene: its biological characteristics and animal
RT   model of local invasion by orthotopic transplantation of the cell
RT   line.";
RL   Oral Oncol. 37:386-392(2001).
//