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Cellosaurus LiSa-2 (CVCL_M821)

[Text version]
Cell line name LiSa-2
Synonyms LISA-2
Accession CVCL_M821
Resource Identification Initiative To cite this cell line use: LiSa-2 (RRID:CVCL_M821)
Comments Characteristics: Can be differentiated into mature adipocytes.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Retroperitoneal space; UBERON=UBERON_0003693.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu348Ser (c.1043T>C); Zygosity=Unspecified (PubMed=26643872).
Disease Pleomorphic liposarcoma (NCIt: C3705)
Pleomorphic liposarcoma (ORDO: Orphanet_99969)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=11093810; DOI=10.1002/1097-0215(20001215)88:6<889::AID-IJC8>3.0.CO;2-N
Wabitsch M., Bruderlein S., Melzner I., Braun M., Mechtersheimer G., Moller P.
LiSa-2, a novel human liposarcoma cell line with a high capacity for terminal adipose differentiation.
Int. J. Cancer 88:889-894(2000)

PubMed=18283285; DOI=10.1038/ijo.2008.10
van Beek E.A., Bakker A.H.F., Kruyt P.M., Vink C., Saris W.H.M., Franssen-van Hal N.L.W., Keijer J.
Comparative expression analysis of isolated human adipocytes and the human adipose cell lines LiSa-2 and PAZ6.
Int. J. Obes. 32:912-921(2008)

PubMed=20197395; DOI=10.1158/1535-7163.MCT-09-0705; PMCID=PMC2837520
Mitchell M.A., Johnson J.E., Pascarelli K., Beeharry N., Chiourea M., Gagos S., Lev D.C., von Mehren M., Kipling D., Broccoli D.
Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres.
Mol. Cancer Ther. 9:682-692(2010)

PubMed=22911243; DOI=10.1155/2012/148614; PMCID=PMC3403520
Stratford E.W., Castro R., Daffinrud J., Skarn M., Lauvrak S., Munthe E., Myklebost O.
Characterization of liposarcoma cell lines for preclinical and biological studies.
Sarcoma 2012:148614.1-148614.9(2012)

PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359
Koelsche C., Renner M., Hartmann W., Brandt R., Lehner B., Waldburger N., Alldinger I., Schmitt T., Egerer G., Penzel R., Wardelmann E., Schirmacher P., von Deimling A., Mechtersheimer G.
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)

PubMed=26643872; DOI=10.18632/oncotarget.6464; PMCID=PMC4767443
Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H.H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P.
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M821
Encyclopedic resources Wikidata; Q54902640
Gene expression databases GEO; GSE3643
GEO; GSM482515
Polymorphism and mutation databases Cosmic; 2307721
Cosmic; 2800522
Progenetix; CVCL_M821
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number18