ID   MA-1 [Human contaminated lymphoma]
AC   CVCL_M665
SY   Ma-1
DR   BioSample; SAMN03151897
DR   cancercelllines; CVCL_M665
DR   Wikidata; Q54903677
RX   PubMed=21837708;
RX   PubMed=23508748;
RX   PubMed=23508779;
RX   PubMed=23907998;
RX   PubMed=24285409;
CC   Problematic cell line: Contaminated. Shown to be a Pfeiffer derivative (PubMed=23907998) and not a mucosa-associated lymphoid tissue (MALT) lymphoma cell line. This finding is disputed by the original authors (PubMed=24285409).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00471.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Arg1171Cys (c.3511C>T); ClinVar=VCV000133518; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C36080; Diffuse large B-cell lymphoma germinal center B-cell type
DI   ORDO; Orphanet_544; Diffuse large B-cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3326 ! Pfeiffer
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 30-01-24; Version: 19
RX   PubMed=21837708; DOI=10.1002/gcc.20910;
RA   Kuo S.-H., Weng W.-H., Chen Z.-H., Hsu P.-N., Wu M.-S., Lin C.-W.,
RA   Jeng H.-J., Yeh K.-H., Tsai H.-J., Chen L.-T., Cheng A.-L.;
RT   "Establishment of a novel MALT lymphoma cell line, Ma-1, from a
RT   patient with t(14;18)(q32;q21)-positive Helicobacter pylori-independent
RT   gastric MALT lymphoma.";
RL   Genes Chromosomes Cancer 50:908-921(2011).
RX   PubMed=23508748; DOI=10.1002/gcc.22051;
RA   Kuo S.-H., Yeh K.-H., Cheng A.-L., Weng W.-H., Chen L.-T.;
RT   "No evidence of IGH-MALT1-translocation in the Ma-1 cell line -- a
RT   reply.";
RL   Genes Chromosomes Cancer 52:593-594(2013).
RX   PubMed=23508779; DOI=10.1002/gcc.22052;
RA   Flossbach L., Barth T.F.E., Moller P.;
RT   "No evidence of IGH-MALT1 translocation in the Ma-1 cell line.";
RL   Genes Chromosomes Cancer 52:591-592(2013).
RX   PubMed=23907998; DOI=10.1002/gcc.22094;
RA   Capes-Davis A., Alston-Roberts C., Kerrigan L., Reid Y.A., Barrett T.,
RA   Burnett E.C., Cooper J.R., Freshney R.I., Healy L.E., Kohara A.,
RA   Korch C.T., Masters J.R.W., Nakamura Y., Nims R.W., Storts D.R.,
RA   Dirks W.G., MacLeod R.A.F., Drexler H.G.;
RT   "Beware imposters: MA-1, a novel MALT lymphoma cell line, is
RT   misidentified and corresponds to Pfeiffer, a diffuse large B-cell
RT   lymphoma cell line.";
RL   Genes Chromosomes Cancer 52:986-988(2013).
RX   PubMed=24285409; DOI=10.1002/gcc.22122;
RA   Kuo S.-H., Tsai H.-J., Weng W.-H., Li C.-C., Yeh K.-H., Chen L.-T.,
RA   Cheng A.-L.;
RT   "Comments on: 'beware imposters: MA-1, a novel MALT lymphoma cell line,
RT   is misidentified and corresponds to Pfeiffer, a diffuse large B-cell
RT   lymphoma cell line-A'. Reply: despite the same 8-code STR, MA-1 and
RT   Pfeiffer are cytogenetically diverse.";
RL   Genes Chromosomes Cancer 53:211-213(2014).