ID   2563
AC   CVCL_M629
DR   BioSample; SAMN03151658
DR   Wikidata; Q54583662
RX   CelloPub=CLPUB00262;
RX   PubMed=66321;
RX   PubMed=6451928;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=6451928; PubMed=20143388). Originally thought to originate from a male patient with a lung adenocarcinoma. The 2563 cell line is said to be derived from the MAC-21 cell line (Cellosaurus=CVCL_M627) which is also HeLa contaminated but which has never been tested for such a contamination.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00032.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 19
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RX   CelloPub=CLPUB00262;
RA   Gold M.;
RT   "A conspiracy of cells. One woman's immortal legacy and the medical
RT   scandal it caused.";
RL   (In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986).
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RX   PubMed=66321; DOI=10.1093/jnci/58.4.863;
RA   Akeson R.;
RT   "Human lung organ-specific antigens on normal lung, lung tumors, and a
RT   lung tumor cell line.";
RL   J. Natl. Cancer Inst. 58:863-869(1977).
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RX   PubMed=6451928; DOI=10.1126/science.6451928;
RA   Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.;
RT   "Cross-contamination of cells in culture.";
RL   Science 212:446-452(1981).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//