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Cellosaurus MAC-21 (CVCL_M627)

[Text version]
Cell line name MAC-21
Synonyms MAC 21
Accession CVCL_M627
Resource Identification Initiative To cite this cell line use: MAC-21 (RRID:CVCL_M627)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative. Originally thought to originate from a male patient with a lung adenocarcinoma. The original MAC-21 cell line was never tested for contamination. See the colorful description of the MAC-21 contamination story in the book from Michael Gold (CelloPub=CLPUB00262).
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

Cailleau R.M.
The establishment of a cell strain (MAC-21) from a mucoid adenocarcinoma of the human lung.
Cancer Res. 20:837-840(1960)

Fuse Y., Price Z.H., Carpenter C.M.
A comparison of the fine structure of cultured MAC-21 and HeLa cells.
Cancer Res. 23:1658-1664(1963)

Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

Encyclopedic resources Wikidata; Q54903951
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number16