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Cellosaurus SH-2 [Human contaminated breast cancer] (CVCL_M622)

[Text version]
Cell line name SH-2 [Human contaminated breast cancer]
Synonyms SH2
Accession CVCL_M622
Resource Identification Initiative To cite this cell line use: SH-2 [Human contaminated breast cancer] (RRID:CVCL_M622)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=6451928; PubMed=20143388). Originally thought to originate from the pleural effusion of a Caucasian female patient with a breast carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00086.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

CLPUB00114
Seman G., Hunter S.J., Dmochowski L.
Two cell lines (SH-2 and SH-3) derived from human breast cancer.
Proc. Am. Assoc. Cancer Res. 16:59-59(1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

CLPUB00262
Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In book) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany; USA (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151757
Encyclopedic resources Wikidata; Q54953196
Entry history
Entry creation05-Nov-2013
Last entry update02-May-2024
Version number19