ID   Rh36
AC   CVCL_M599
SY   RH36; RH-36; Birch; BIRCH
DR   cancercelllines; CVCL_M599
DR   Cell_Model_Passport; SIDM01350
DR   Cosmic; 724814
DR   Cosmic; 802042
DR   DepMap; ACH-001751
DR   GEO; GSM186453
DR   GEO; GSM186454
DR   GEO; GSM1676312
DR   GEO; GSM1701646
DR   PRIDE; PXD007755
DR   Progenetix; CVCL_M599
DR   Wikidata; Q54950343
RX   CelloPub=CLPUB00569;
RX   PubMed=10602515;
RX   PubMed=11051265;
RX   PubMed=12068308;
RX   PubMed=23882450;
RX   PubMed=26351324;
RX   PubMed=28196595;
RX   PubMed=31448612;
WW   https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: MD Anderson Cell Lines Project.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000012601; Zygosity=Unspecified (PubMed=12068308; DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: Exosome proteome analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
ST   Source(s): COG
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 12,13
ST   D16S539: 11,13
ST   D18S51: 16
ST   D19S433: 14,15
ST   D21S11: 31,32
ST   D2S1338: 18
ST   D3S1358: 14,16
ST   D5S818: 13
ST   D7S820: 10,11
ST   D8S1179: 13
ST   FGA: 25
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 14,18
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 05-10-23; Version: 21
//
RX   CelloPub=CLPUB00569;
RA   Dickman P.S., Tsokos M.G., Triche T.J.;
RT   "Biology of rhabdomyosarcoma: cell culture, xenografts, and animal
RT   models.";
RL   (In) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton (1991).
//
RX   PubMed=10602515; DOI=10.1038/sj.onc.1203168;
RA   DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.;
RT   "Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and
RT   primary rhabdomyosarcomas but not Wilms' tumors.";
RL   Oncogene 18:7559-7565(1999).
//
RX   PubMed=11051265;
RA   Petak I., Douglas L., Tillman D.M., Vernes R., Houghton J.A.;
RT   "Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced
RT   apoptosis and highly sensitive to TRAIL-induced apoptosis.";
RL   Clin. Cancer Res. 6:4119-4127(2000).
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies H., Bignell G.R., Cox C., Stephens P.J., Edkins S., Clegg S.,
RA   Teague J.W., Woffendin H., Garnett M.J., Bottomley W., Davis N.,
RA   Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J.,
RA   Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S.,
RA   Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C.S.,
RA   Shipley J.M., Hargrave D., Pritchard-Jones K., Maitland N.J.,
RA   Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A.,
RA   Flanagan A.M., Nicholson A., Ho J.W.C., Leung S.Y., Yuen S.T.,
RA   Weber B.L., Seigler H.F., Darrow T.L., Paterson H.F., Marais R.,
RA   Marshall C.J., Wooster R., Stratton M.R., Futreal P.A.;
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=23882450; DOI=10.3389/fonc.2013.00183;
RA   Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G.,
RA   Linardic C.M.;
RT   "Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research:
RT   utility and pitfalls.";
RL   Front. Oncol. 3:183.1-183.12(2013).
//
RX   PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074;
RA   Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E.,
RA   Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J.,
RA   Harris E., Monks A., Morris J.;
RT   "Sarcoma cell line screen of oncology drugs and investigational agents
RT   identifies patterns associated with gene and microRNA expression.";
RL   Mol. Cancer Ther. 14:2452-2462(2015).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=31448612; DOI=10.1021/acs.jproteome.9b00157;
RA   Rammal G., Fahs A., Kobeissy F., Mechref Y., Zhao J.-F., Zhu R.,
RA   Diab-Assaf M., Saab R., Ghayad S.E.;
RT   "Proteomic profiling of rhabdomyosarcoma-derived exosomes yield
RT   insights into their functional role in paracrine signaling.";
RL   J. Proteome Res. 18:3567-3579(2019).
//