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Cellosaurus HONE-1/CPT30R (CVCL_M596)

[Text version]
Cell line name HONE-1/CPT30R
Synonyms CPT30R
Accession CVCL_M596
Resource Identification Initiative To cite this cell line use: HONE-1/CPT30R (RRID:CVCL_M596)
Comments Problematic cell line: Parent cell line (HONE-1) seems to bear part of the HeLa genomic sequence and may be a derivative of HeLa and another cell of unknown origin.
Characteristics: Partial revertant of the CPT30 camptothecin-resistant subline.
Selected for resistance to: ChEBI; CHEBI:27656; Camptothecin (CPT).
Sequence variations
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M595 (HONE-1/CPT30)
Sex of cell Male
Category Cancer cell line

Chang J.-Y., Liu J.-F., Juang S.-H., Liu T.-W., Chen L.-T.
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.
Cancer Res. 62:3716-3721(2002)

Cell line databases/resources cancercelllines; CVCL_M596
Encyclopedic resources Wikidata; Q54890149
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number12