ID   CM2005.1
AC   CVCL_M592
SY   CM2005_1
DR   cancercelllines; CVCL_M592
DR   Cosmic; 2639620
DR   Wikidata; Q54813726
RX   PubMed=17947278;
RX   PubMed=25722211;
RX   PubMed=28903377;
CC   Characteristics: Highly pigmented.
CC   Doubling time: ~35 hours (PubMed=17947278).
CC   Karyotypic information: Has lost chromosome Y.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=25722211).
ST   Source(s): PubMed=25722211
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11,14
ST   D16S539: 12,13
ST   D18S51: 14,16
ST   D19S433: 16.2
ST   D21S11: 29,30
ST   D2S1338: 17,25
ST   D3S1358: 17
ST   D5S818: 11,12
ST   D7S820: 12,14
ST   D8S1179: 14,15
ST   FGA: 20,23
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C4550; Conjunctival melanoma
DI   ORDO; Orphanet_617910; Conjunctival malignant melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   84Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 13
//
RX   PubMed=17947278; DOI=10.1136/bjo.2006.110841; PMCID=PMC2095439;
RA   Keijser S., Maat W., Missotten G.S., de Keizer R.J.W.;
RT   "A new cell line from a recurrent conjunctival melanoma.";
RL   Br. J. Ophthalmol. 91:1566-1567(2007).
//
RX   PubMed=25722211; DOI=10.1167/iovs.14-15239;
RA   de Waard N.E., Cao J.-F., McGuire S.P., Kolovou P.E., Jordanova E.S.,
RA   Ksander B.R., Jager M.J.;
RT   "A murine model for metastatic conjunctival melanoma.";
RL   Invest. Ophthalmol. Vis. Sci. 56:2325-2333(2015).
//
RX   PubMed=28903377; DOI=10.18632/oncotarget.18039; PMCID=PMC5589616;
RA   Cao J.-F., Brouwer N.J., Richards K.E., Marinkovic M., van Duinen S.,
RA   Hurkmans D., Verdegaal E.M.E., Jordanova E.S., Jager M.J.;
RT   "PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in
RT   conjunctival melanoma.";
RL   Oncotarget 8:54722-54734(2017).
//