ID   STHdhQ109
AC   CVCL_M589
SY   STHdhQ109/Q109
DR   Wikidata; Q54970578
RX   PubMed=21985783;
CC   Characteristics: From a transgenic mouse containing homozygous HTT loci with a humanized exon 1 containing 109 polyglutamine repeats (PubMed=21985783).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Brain, forebrain, striatum; UBERON=UBERON_0002435.
CC   Cell type: Neuron; CL=CL_0000540.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
AG   14FD
CA   Transformed cell line
DT   Created: 05-11-13; Last updated: 10-09-24; Version: 11
//
RX   PubMed=21985783; DOI=10.1172/JCI57552; PMCID=PMC3223861;
RA   Keryer G., Pineda J.R., Liot G., Kim J., Dietrich P., Benstaali C.,
RA   Smith K., Cordelieres F.P., Spassky N., Ferrante R.J., Dragatsis I.,
RA   Saudou F.;
RT   "Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is
RT   altered in Huntington disease.";
RL   J. Clin. Invest. 121:4372-4382(2011).
//