ID   HBL-2 [Human B-cell lymphoma]
AC   CVCL_M573
DR   cancercelllines; CVCL_M573
DR   IARC_TP53; 5997
DR   Wikidata; Q54881431
RX   PubMed=3899542;
RX   PubMed=8558920;
RX   PubMed=8878455;
CC   Population: Chinese.
CC   Doubling time: ~20 hours (PubMed=3899542).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Arg (c.838A>C); ClinVar=VCV000926213; Zygosity=Unspecified (PubMed=8878455).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp281Gly (c.842A>G); ClinVar=VCV000141141; Zygosity=Unspecified (PubMed=8878455).
CC   Misspelling: AKA96-2; IARC_TP53=5997; Note=Not really a misspelling but an assignment of a name based on first author of publication and date because assignment of correct cell line name was not done correctly.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C3457; B-cell non-Hodgkin lymphoma
DI   ORDO; Orphanet_171915; B-cell non-Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   17Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 16
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RX   PubMed=3899542;
RA   Peng H.-W., Chong L.-L., Chiang H., Chiang B.N.;
RT   "Establishment and characterization of a new human lymphoma-derived
RT   cell line -- HBL-2.";
RL   Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 18:79-85(1985).
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RX   PubMed=8558920;
RA   Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M.,
RA   Quentmeier H., Drexler H.G.;
RT   "The (2;5)(p23;q35) translocation in cell lines derived from malignant
RT   lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.";
RL   Leukemia 10:142-149(1996).
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RX   PubMed=8878455; DOI=10.1111/j.1349-7006.1996.tb02122.x; PMCID=PMC5921203;
RA   Akasaka T., Muramatsu M., Kadowaki N., Ohno H., Ishizaki K.,
RA   Yamabe H., Fukuhara S., Okuma M.;
RT   "p53 mutation in B-cell lymphoid neoplasms with reference to oncogene
RT   rearrangements associated with chromosomal translocations.";
RL   Jpn. J. Cancer Res. 87:930-937(1996).
//