Cellosaurus cell line L-872 (CVCL

Cross-references
Cell line name	L-872
Accession	CVCL_M347
Resource Identification Initiative	To cite this cell line use: L-872 (RRID:CVCL_M347)
Comments	Derived from site: In situ; Bone, rib; UBERON=UBERON_0002228.
Sequence variations	Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=16631476). Mutation; HGNC; HGNC:11998; TP53; Simple; p.His214Arg (c.641A>G); ClinVar=VCV000376615; Zygosity=Unspecified (PubMed=26428435).
Disease	Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	20Y
Category	Cancer cell line
Publications	PubMed=16631476; DOI=10.1016/j.cancergencyto.2005.11.006 Szuhai K., IJszenga M., Tanke H.J., Rosenberg C., Hogendoorn P.C.W. Molecular cytogenetic characterization of four previously established and two newly established Ewing sarcoma cell lines. Cancer Genet. Cytogenet. 166:173-179(2006) PubMed=26428435; DOI=10.1016/j.ejca.2015.08.020 Sand L.G.L., Scotlandi K., Berghuis D., Snaar-Jagalska B.E., Picci P., Schmidt T., Szuhai K., Hogendoorn P.C.W. CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients. Eur. J. Cancer 51:2624-2633(2015)
Cell line databases/resources	cancercelllines; CVCL_M347
Encyclopedic resources	Wikidata; Q54900882
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	14