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Cellosaurus XP25BE LCL (CVCL_M289)

[Text version]
Cell line name XP25BE LCL
Synonyms Xeroderma Pigmentosum 25 BEthesda LCL; GM04490; KR04490
Accession CVCL_M289
Resource Identification Initiative To cite this cell line use: XP25BE LCL (RRID:CVCL_M289)
Comments Population: African American.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 12816; XPC; Unexplicit; IVS11-1_IVS11-2delAG; Zygosity=Homozygous (PubMed=16081512).
  • Mutation; HGNC; 12816; XPC; Unexplicit; IVS11-6_IVS11-7insCC; Zygosity=Homozygous (PubMed=16081512).
Disease Xeroderma pigmentosum, complementation group C (NCIt: C114770)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_M288 ! XP25BE
Sex of cell Female
Age at sampling 7Y
Category Transformed cell line
Publications

PubMed=16081512; DOI=10.1093/carcin/bgi204
Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H., Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J., Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A., Kraemer K.H.
Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.
Carcinogenesis 27:84-94(2006)

Cross-references
Cell line collections (Providers) Coriell; GM04490
Cell line databases/resources CLO; CLO_0019668
Biological sample resources BioSample; SAMN00795297
Encyclopedic resources Wikidata; Q54838537
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number15