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Cellosaurus HuCC-A1 (CVCL_M255)

[Text version]
Cell line name HuCC-A1
Synonyms HuCCA-1; HuCCA1
Accession CVCL_M255
Resource Identification Initiative To cite this cell line use: HuCC-A1 (RRID:CVCL_M255)
Comments Population: Southeast Asian; Thai.
Doubling time: ~55 hours (PubMed=1666951).
Omics: Secretome proteome analysis.
Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Opisthorchis viverrini-related cholangiocarcinoma (NCIt: C27769)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_HF36 (HuCC-A1Nu)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1657

Markers:
AmelogeninX
CSF1PO10,11
D5S81812
D7S82010,11
D13S3178
D16S53911,12
TH019
TPOX9
vWA14,19

Run an STR similarity search on this cell line
Web pages http://www2.cri.or.th/lab/biochemistry/res_act
Publications

PubMed=1666951
Sirisinha S., Tengchaisri T., Boonpucknavig S., Prempracha N., Ratanarapee S., Pausawasdi A.
Establishment and characterization of a cholangiocarcinoma cell line from a Thai patient with intrahepatic bile duct cancer.
Asian Pac. J. Allergy Immunol. 9:153-157(1991)

PubMed=9031402
Sriurairatana S., Tengchaisri T., Sirisinha S.
Ultrastructural characteristics of liver fluke associated human cholangiocarcinoma cell lines.
Southeast Asian J. Trop. Med. Public Health 27:57-62(1996)

PubMed=12587840
Panichakul T., Wanun T., Reutrakul V., Sirisinha S.
Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.
Asian Pac. J. Allergy Immunol. 20:167-173(2002)

PubMed=15048994; DOI=10.1002/pmic.200300651
Srisomsap C., Sawangareetrakul P., Subhasitanont P., Panichakul T., Keeratichamroen S., Lirdprapamongkol K., Chokchaichamnankit D., Sirisinha S., Svasti J.
Proteomic analysis of cholangiocarcinoma cell line.
Proteomics 4:1135-1144(2004)

PubMed=16475706
Panichakul T., Intachote P., Wongkajornsilp A., Sripa B., Sirisinha S.
Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis.
Anticancer Res. 26:259-265(2006)

PubMed=20069059; DOI=10.1155/2010/437143; PMCID=PMC2801507
Srisomsap C., Sawangareetrakul P., Subhasitanont P., Chokchaichamnankit D., Chiablaem K., Bhudhisawasdi V., Wongkham S., Svasti J.
Proteomic studies of cholangiocarcinoma and hepatocellular carcinoma cell secretomes.
J. Biomed. Biotechnol. 2010:437143.1-437143.18(2010)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=31077409; DOI=10.1002/hep.30704
Sittithumcharee G., Suppramote O., Vaeteewoottacharn K., Sirisuksakun C., Jamnongsong S., Laphanuwat P., Suntiparpluacha M., Matha A., Chusorn P., Buraphat P., Kakanaporn C., Charngkaew K., Silsirivanit A., Korphaisarn K., Limsrichamrern S., Tripatara P., Pairojkul C., Wongkham S., Sampattavanich S., Okada S., Jirawatnotai S.
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1657
Chemistry resources ChEMBL-Cells; CHEMBL4513113
ChEMBL-Targets; CHEMBL4513129
PubChem_Cell_line; CVCL_M255
Encyclopedic resources Wikidata; Q54896723
Entry history
Entry creation05-Nov-2013
Last entry update02-May-2024
Version number19