Cellosaurus HepAD38 (CVCL_M177)
Cell line name | HepAD38 |
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Synonyms | Hep AD38; HepG2 AD38; HepG2-AD38; Hep G2 AD 38; AD-38; AD38 |
Accession | CVCL_M177 |
Resource Identification Initiative | To cite this cell line use: HepAD38 (RRID:CVCL_M177) |
Comments | Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12077. Population: Caucasian. Biotechnology: Used in a bioassay that permits the large-scale screening of compound libraries for inhibitors of HBV replication. Virology: Inducibly expresses a hepatitis B virus (HBV) genome under the control of a tet operator/CMV promoter. Upon removal of tetracycline the cell line produces viral RNA and secrete virus-like particles into the supernatant. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
Sequence variations |
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Disease | Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0027 (Hep-G2) |
Sex of cell | Male |
Age at sampling | 15Y |
Category | Cancer cell line |
Publications | PubMed=9257747; DOI=10.1128/AAC.41.8.1715 Patent=US5723319 PubMed=9875378 PubMed=21331898; DOI=10.1385/1-59259-245-7:43 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_M177 |
Anatomy/cell type resources | BTO; BTO:0006298 |
Encyclopedic resources | Wikidata; Q54882829 |
Entry history | |
Entry creation | 06-May-2013 |
Last entry update | 05-Oct-2023 |
Version number | 21 |