ID   HC-AFW1
AC   CVCL_M172
SY   HCAFW1
DR   cancercelllines; CVCL_M172
DR   GEO; GSE29283
DR   Progenetix; CVCL_M172
DR   Wikidata; Q54881474
RX   PubMed=22666492;
RX   PubMed=26310804;
CC   Doubling time: 40 hours (PubMed=22666492).
CC   Sequence variation: Gene deletion; HGNC; HGNC:2625; CYP2D6; Zygosity=Heterozygous (PubMed=26310804).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Val22_Phe70del; Zygosity=Heterozygous (PubMed=22666492).
CC   Omics: CNV analysis.
DI   NCIt; C7955; Childhood hepatocellular carcinoma
DI   ORDO; Orphanet_33402; Pediatric hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   4Y6M
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 19-12-24; Version: 15
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RX   PubMed=22666492; DOI=10.1371/journal.pone.0038223; PMCID=PMC3364222;
RA   Armeanu-Ebinger S., Wenz J., Seitz G., Leuschner I., Handgretinger R.,
RA   Mau-Holzmann U.A., Bonin M., Sipos B., Fuchs J., Warmann S.W.;
RT   "Characterisation of the cell line HC-AFW1 derived from a pediatric
RT   hepatocellular carcinoma.";
RL   PLoS ONE 7:E38223-E38223(2012).
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RX   PubMed=26310804; DOI=10.1124/dmd.115.064667;
RA   Braeuning A., Thomas M., Hofmann U., Vetter S., Zeller E., Petzuch B.,
RA   Johanning J., Schroth W., Weiss T.S., Zanger U.M., Schwarz M.;
RT   "Comparative analysis and functional characterization of HC-AFW1
RT   hepatocarcinoma cells: cytochrome P450 expression and induction by
RT   nuclear receptor agonists.";
RL   Drug Metab. Dispos. 43:1781-1787(2015).
//