ID   CHLA-266
AC   CVCL_M149
SY   CHLA266
DR   cancercelllines; CVCL_M149
DR   Cell_Model_Passport; SIDM01537
DR   DepMap; ACH-001031
DR   Wikidata; Q54812496
RX   CelloPub=CLPUB00418;
RX   PubMed=20922763;
RX   PubMed=22120608;
WW   https://www.cccells.org/tables/Brain_N.php
WW   http://www.pptpinvitro.org/cell_lines_panel.php
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
CC   Doubling time: 40 hours (CelloPub=CLPUB00418); 45 hours (PubMed=22120608); 50 hours (PubMed=20922763).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Brain, posterior fossa; UBERON=UBERON_0008788.
ST   Source(s): COG; PubMed=20922763; PubMed=22120608
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 9,10
ST   D16S539: 10,12
ST   D18S51: 17,19
ST   D19S433: 13,14
ST   D21S11: 29
ST   D2S1338: 20
ST   D3S1358: 15,18
ST   D5S818: 10,12
ST   D7S820: 10,12
ST   D8S1179: 10,14
ST   FGA: 23,24
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C6906; Atypical teratoid/rhabdoid tumor
DI   ORDO; Orphanet_99966; Atypical teratoid rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   2Y6M
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 05-10-23; Version: 16
//
RX   CelloPub=CLPUB00418;
RA   Xu J.-Y., Erdreich-Epstein A., Biegel J.A., Reynolds C.P.;
RT   "Fenretinide combined with thiotepa is active against 3 newly
RT   established atypical teratoid rhabdoid tumor cell lines that manifest
RT   high-level multidrug resistance.";
RL   Cancer Res. 68 Suppl. 9:3743-3743(2008).
//
RX   PubMed=20922763; DOI=10.1002/pbc.22801;
RA   Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J.,
RA   Reynolds C.P.;
RT   "National Cancer Institute pediatric preclinical testing program:
RT   model description for in vitro cytotoxicity testing.";
RL   Pediatr. Blood Cancer 56:239-249(2011).
//
RX   PubMed=22120608; DOI=10.1007/s11060-011-0756-5;
RA   Xu J.-Y., Erdreich-Epstein A., Gonzalez-Gomez I., Melendez E.Y.,
RA   Smbatyan G., Moats R.A., Rosol M., Biegel J.A., Reynolds C.P.;
RT   "Novel cell lines established from pediatric brain tumors.";
RL   J. Neurooncol. 107:269-280(2012).
//