| Cell line name |
LNCaP C-51 |
|---|
| Synonyms |
LNCaP-C51 C-51; C51 |
|---|
| Accession |
CVCL_M130 |
|---|
| Resource Identification Initiative |
To cite this cell line use: LNCaP C-51 (RRID:CVCL_M130) |
|---|
| Comments |
Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
|
|---|
| Disease |
Prostate carcinoma (NCIt: C4863) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_M129 (LNCaP C-33) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
50Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=11705865
Karan D., Schmied B.M., Dave B.J., Wittel U.A., Lin M.-F., Batra S.K.
Decreased androgen-responsive growth of human prostate cancer is associated with increased genetic alterations.
Clin. Cancer Res. 7:3472-3480(2001) PubMed=11870800; DOI=10.1002/pros.10054
Igawa T., Lin F.-F., Lee M.-S., Karan D., Batra S.K., Lin M.-F.
Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model.
Prostate 50:222-235(2002) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_M130
|
|---|
| Encyclopedic resources |
Wikidata; Q54902823
|
|---|
| Entry history |
|---|
| Entry creation | 06-May-2013 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 17 |
|---|
