Cellosaurus cell line UD-SCC-7B (CVCL

Cellosaurus UD-SCC-7B (CVCL_M119)

Cross-references
Cell line name	UD-SCC-7B
Synonyms	UD-SCC 7B; UD-SCC7B; University of Dusseldorf-Squamous Cell Carcinoma-7B
Accession	CVCL_M119
Resource Identification Initiative	To cite this cell line use: UD-SCC-7B (RRID:CVCL_M119)
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=15495191; PubMed=18487078). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Unspecified (PubMed=18487078).
Disease	Oropharyngeal squamous cell carcinoma (NCIt: C8181) Squamous cell carcinoma of the oropharynx (ORDO: Orphanet_500478)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_M118 ! UD-SCC-7A CVCL_YD75 ! UD-SCC-7C
Category	Cancer cell line
Publications	PubMed=15495191; DOI=10.1002/gcc.20119 Raschke S., Balz V., Efferth T., Schulz W.A., Florl A.R. Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines. Genes Chromosomes Cancer 42:58-67(2005) PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006 Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L., Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U., Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H., Balz V. Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma. Oral Oncol. 44:1100-1109(2008)
Cell line databases/resources	cancercelllines; CVCL_M119
Encyclopedic resources	Wikidata; Q54990113
Polymorphism and mutation databases	Cosmic; 932286
Entry history
Entry creation	06-May-2013
Last entry update	19-Dec-2024
Version number	11