Cellosaurus cell line SKOV-3/RFP (CVCL

Cross-references
Cell line name	SKOV-3/RFP
Accession	CVCL_M090
Resource Identification Initiative	To cite this cell line use: SKOV-3/RFP (RRID:CVCL_M090)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease	Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0532 (SK-OV-3)
Sex of cell	Female
Age at sampling	64Y
Category	Cancer cell line
Cell line collections (Providers)	Cell_Biolabs; AKR-253 - Discontinued
Cell line databases/resources	cancercelllines; CVCL_M090
Encyclopedic resources	Wikidata; Q54954764
Entry history
Entry creation	06-May-2013
Last entry update	19-Dec-2024
Version number	22