Cellosaurus logo
expasy logo

Cellosaurus MWCL-1 (CVCL_M086)

[Text version]
Cell line name MWCL-1
Synonyms MWCL.1; MWCL1
Accession CVCL_M086
Resource Identification Initiative To cite this cell line use: MWCL-1 (RRID:CVCL_M086)
Comments Omics: Array-based CGH.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
Disease Waldenstrom macroglobulinemia (NCIt: C80307)
Waldenstrom macroglobulinemia (ORDO: Orphanet_33226)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VJ31 (MWCL-1/BR)CVCL_VJ32 (MWCL-1/IR)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
Publications

PubMed=21415268; DOI=10.1182/blood-2010-12-326868
Hodge L.S., Novak A.J., Grote D.M., Braggio E., Ketterling R.P., Manske M.K., Price-Troska T.L., Ziesmer S.C., Fonseca R., Witzig T.E., Morice W.G. 2nd, Gertz M.A., Ansell S.M.
Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1.
Blood 117:e190-e197(2011)

PubMed=22950966; DOI=10.3109/10428194.2012.727418
Drexler H.G., Chen S., MacLeod R.A.F.
Would the real Waldenstrom cell line please stand up?
Leuk. Lymphoma 54:224-226(2013)

PubMed=23321251; DOI=10.1182/blood-2012-09-454355; PMCID=PMC3596964
Xu L., Hunter Z.R., Yang G., Zhou Y.-S., Cao Y., Liu X., Morra E., Trojani A., Greco A., Arcaini L., Varettoni M., Brown J.R., Tai Y.-T., Anderson K.C., Munshi N.C., Patterson C.J., Manning R.J., Tripsas C.K., Lindeman N.I., Treon S.P.
MYD88 L265P in Waldenstrom macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction.
Blood 121:2051-2058(2013)

PubMed=24189269; DOI=10.1038/labinvest.2013.129
Wada N., Zhan M.-S., Hori Y., Honma K., Ikeda J.-i., Morii E.
Characterization of subpopulation lacking both B-cell and plasma cell markers in Waldenstrom macroglobulinemia cell line.
Lab. Invest. 94:79-88(2014)

PubMed=25382610; DOI=10.1038/bcj.2014.74; PMCID=PMC5424099
Chitta K.S., Paulus A., Caulfield T.R., Akhtar S., Blake M.K.K., Ailawadhi S., Knight J., Heckman M.G., Pinkerton A.B., Chanan-Khan A.A.
Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenstroms macroglobulinemia.
Blood Cancer J. 4:e260.1-e260.10(2014)

PubMed=25853860; DOI=10.1371/journal.pone.0122338; PMCID=PMC4390194
Paulus A., Chitta K.S., Wallace P.K., Advani P.P., Akhtar S., Blake M.K.K., Ailawadhi S., Chanan-Khan A.A.
Immunophenotyping of Waldenstroms macroglobulinemia cell lines reveals distinct patterns of surface antigen expression: potential biological and therapeutic implications.
PLoS ONE 10:E0122338-E0122338(2015)

Cross-references
Cell line databases/resources CLO; CLO_0037225
cancercelllines; CVCL_M086
LINCS_HMS; 51098
LINCS_LDP; LCL-2109
Encyclopedic resources Wikidata; Q28914904
Polymorphism and mutation databases Cosmic; 1762457
Cosmic; 2645644
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number16