Cellosaurus cell line BT-20/nKR (CVCL

Cross-references
Cell line name	BT-20/nKR
Accession	CVCL_M061
Resource Identification Initiative	To cite this cell line use: BT-20/nKR (RRID:CVCL_M061)
Comments	Group: Triple negative breast cancer (TNBC) cell line. Population: Caucasian. Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro539Arg (c.1616C>G); ClinVar=VCV000376243; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ile388Ser (c.1163T>G); ClinVar=VCV000665312; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:9884; RB1; Simple; p.Pro515Leu (c.1544C>T); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Homozygous (from parent cell line).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0178 (BT-20)
Sex of cell	Female
Age at sampling	74Y
Category	Cancer cell line
Cell line collections (Providers)	KCLB; 60071
Cell line databases/resources	cancercelllines; CVCL_M061
Encyclopedic resources	Wikidata; Q54798454
Entry history
Entry creation	06-May-2013
Last entry update	19-Dec-2024
Version number	18