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Cellosaurus PC-3/nKR (CVCL_M060)

[Text version]
Cell line name PC-3/nKR
Synonyms PC3/nKR
Accession CVCL_M060
Resource Identification Initiative To cite this cell line use: PC-3/nKR (RRID:CVCL_M060)
Comments Population: Caucasian.
Characteristics: Compared to the parent cell line, has an increased cell migration capability and a higher number of invaded cell. Established from nude mice that were implanted with the parent cell line without anti-NK treatment.
Omics: Secretome proteome analysis.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): KCLB=60069

Markers:
AmelogeninX
CSF1PO11
D3S135816
D5S81813
D7S8208,11
D13S31711
FGA24
TH016,7
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=31404090; DOI=10.1371/journal.pone.0220807; PMCID=PMC6690527
Jeon J.M., Kwon O.K., Na A.-Y., Sung E.J., Cho I.J., Kim M., Yea S.S., Chun S.Y., Lee J.H., Ha Y.-S., Kwon T.G., Lee S.
Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells.
PLoS ONE 14:E0220807-E0220807(2019)

Cross-references
Cell line collections (Providers) KCLB; 60069
Cell line databases/resources cancercelllines; CVCL_M060
Encyclopedic resources Wikidata; Q54938421
Proteomic databases PRIDE; PXD008184
Entry history
Entry creation06-May-2013
Last entry update02-May-2024
Version number17