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Cellosaurus HEK293/rABCC6 (CVCL_LN33)

[Text version]
Cell line name HEK293/rABCC6
Accession CVCL_LN33
Resource Identification Initiative To cite this cell line use: HEK293/rABCC6 (RRID:CVCL_LN33)
Comments Genetic integration: Method=Transfection/transduction; Gene=RGD; 620268; Abcc6.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Omics: Metabolome analysis.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U427 (Flp-In-T-REx-293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=24277820; DOI=10.1073/pnas.1319582110; PMCID=PMC3864344
Jansen R.S., Kucukosmanoglu A., de Haas M., Sapthu S., Otero J.A., Hegman I.E.M., Bergen A.A.B., Gorgels T.G.M.F., Borst P., van de Wetering K.
ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release.
Proc. Natl. Acad. Sci. U.S.A. 110:20206-20211(2013)

Cross-references
Encyclopedic resources Wikidata; Q54882478
Metabolomic databases MetaboLights; MTBLS61
Entry history
Entry creation15-Nov-2017
Last entry update10-Sep-2024
Version number10