ID   MET-2
AC   CVCL_LN10
SY   MET2
DR   CancerTools; 153569
DR   GEO; GSM2611470
DR   GEO; GSM2611471
DR   GEO; GSM2611472
DR   Wikidata; Q54905318
DR   Ximbio; 153569
RX   PubMed=10772384;
RX   PubMed=11121147;
RX   PubMed=30202019;
RX   PubMed=31336867;
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Hand, skin; UBERON=UBERON_0001519.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): PubMed=31336867
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 8,12
ST   D16S539: 11,13
ST   D18S51: 18,19
ST   D19S433: 14
ST   D21S11: 30.2,33.2
ST   D2S1338: 17,21
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 7,8
ST   D8S1179: 12,15
ST   FGA: 24
ST   TH01: 9.3
ST   TPOX: 9,11
ST   vWA: 18,19
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_LN09 ! MET-1
OI   CVCL_LN11 ! MET-3
OI   CVCL_LN12 ! MET-4
OI   CVCL_LN13 ! PM-1 [Human oral dysplasia]
OI   CVCL_VJ50 ! SCCT9
SX   Male
AG   46Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 30-01-24; Version: 8
//
RX   PubMed=10772384; DOI=10.1034/j.1600-0625.2000.009002104.x;
RA   Proby C.M., Purdie K.J., Sexton C.J., Purkis P., Navsaria H.A.,
RA   Stables J.N., Leigh I.M.;
RT   "Spontaneous keratinocyte cell lines representing early and advanced
RT   stages of malignant transformation of the epidermis.";
RL   Exp. Dermatol. 9:104-117(2000).
//
RX   PubMed=11121147; DOI=10.1046/j.1523-1747.2000.00173.x;
RA   Popp S., Waltering S., Holtgreve-Grez H., Jauch A., Proby C.M.,
RA   Leigh I.M., Boukamp P.;
RT   "Genetic characterization of a human skin carcinoma progression model:
RT   from primary tumor to metastasis.";
RL   J. Invest. Dermatol. 115:1095-1103(2000).
//
RX   PubMed=30202019; DOI=10.1038/s41467-018-06027-1; PMCID=PMC6131170;
RA   Inman G.J., Wang J., Nagano A., Alexandrov L.B., Purdie K.J.,
RA   Taylor R.G., Sherwood V., Thomson J., Hogan S., Spender L.C.,
RA   South A.P., Stratton M.R., Chelala C., Harwood C.A., Proby C.M.,
RA   Leigh I.M.;
RT   "The genomic landscape of cutaneous SCC reveals drivers and a novel
RT   azathioprine associated mutational signature.";
RL   Nat. Commun. 9:3667.1-3667.14(2018).
//
RX   PubMed=31336867; DOI=10.3390/ijms20143428; PMCID=PMC6678499;
RA   Hassan S., Purdie K.J., Wang J., Harwood C.A., Proby C.M.,
RA   Pourreyron C., Mladkova N., Nagano A., Dhayade S., Athineos D.,
RA   Caley M., Mannella V., Blyth K., Inman G.J., Leigh I.M.;
RT   "A Unique panel of patient-derived cutaneous squamous cell carcinoma
RT   cell lines provides a preclinical pathway for therapeutic testing.";
RL   Int. J. Mol. Sci. 20:3428.1-3428.26(2019).
//