Cellosaurus logo
expasy logo

Cellosaurus MaPaC-HS-77 (CVCL_LM84)

[Text version]
Cell line name MaPaC-HS-77
Synonyms MAPAC-HS-77; MAPACHS77; MaPac-77; P4-CL; CL4
Accession CVCL_LM84
Secondary accession CVCL_A1QN
Resource Identification Initiative To cite this cell line use: MaPaC-HS-77 (RRID:CVCL_LM84)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 71 hours (PubMed=33087752); ~2 days (DSMZ=ACC-814).
Omics: Array-based CGH.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (PubMed=33087752; DepMap=ACH-002672).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala159Asp (c.476C>A); ClinVar=VCV001026335; Zygosity=Homozygous (PubMed=33087752; DepMap=ACH-002672).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-814; PubMed=33087752

Markers:
AmelogeninX
CSF1PO11
D2S133817,23
D3S135814
D5S81812,13
D7S82010,11 (DSMZ=ACC-814)
11,12 (PubMed=33087752)
D8S117913,14
D13S31711,13 (DSMZ=ACC-814)
14,16 (PubMed=33087752)
D16S5399,11
D18S5117
D19S43312,15
D21S1128
FGA19,23
Penta D13
Penta E11,12
TH016,9.3
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=33087752; DOI=10.1038/s41598-020-74797-0
Hirsch D., Seyfried S., Staib T., Fiedler D., Sauer C., Ried T., Witt S., Rueckert F., Gaiser T.
Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers.
Sci. Rep. 10:17895-17895(2020)

Cross-references
Cell line collections (Providers) DSMZ; ACC-814
Cell line databases/resources cancercelllines; CVCL_LM84
DepMap; ACH-002672
DSMZCellDive; ACC-814
Encyclopedic resources Wikidata; Q54904006
Gene expression databases GEO; GSM4563058
Entry history
Entry creation15-Nov-2017
Last entry update02-May-2024
Version number9