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Cellosaurus 170-MG-BA (CVCL_LM81)

[Text version]
Cell line name 170-MG-BA
Synonyms 170MGBA
Accession CVCL_LM81
Resource Identification Initiative To cite this cell line use: 170-MG-BA (RRID:CVCL_LM81)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 24 hours (PubMed=30509096); ~40-60 hours (DSMZ=ACC-804).
Omics: Array-based CGH.
Derived from site: In situ; Brain, temporal lobe; UBERON=UBERON_0001871.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (DepMap=ACH-002680).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Thr (c.832C>A); ClinVar=VCV000376643; Zygosity=Homozygous (DepMap=ACH-002680).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-804

Markers:
AmelogeninX
CSF1PO12,13
D2S133820
D3S135818
D5S81811,12
D7S8208,12
D8S117912,13
D13S3178,11
D16S5399,10
D18S5112,19
D19S43314,15
D21S1131,31.2
FGA23,25
Penta D11,12
Penta E17
TH016,8
TPOX8,11
vWA15,20

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Publications

PubMed=30509096; DOI=10.4149/neo_2018_180427N278
MacLeod R.A.F., Schneider B., Sivakova I., Nagel S., Dirks W.G., Mraz P., Kubikova E., Perzelova A.
High level EGFR amplification in a newly established glioblastoma cell line 170-MG-BA.
Neoplasma 66:109-117(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-804
Cell line databases/resources DepMap; ACH-002680
DSMZCellDive; ACC-804
Encyclopedic resources Wikidata; Q54582330
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number10