Cellosaurus logo
expasy logo

Cellosaurus LuKII (CVCL_LK86)

[Text version]
Cell line name LuKII
Synonyms Luk II
Accession CVCL_LK86
Resource Identification Initiative To cite this cell line use: LuKII (RRID:CVCL_LK86)
Comments Problematic cell line: Misidentified. Originally thought to derive from RPMI-8866 but, based on differences in phosphoglucomutase-1 isozyme fingerprints, was determined not to be originating from that cell line (PubMed=6160588).
Characteristics: Produces TNF.
Cell type: B-cell; CL=CL_0000236.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line

PubMed=6160588; DOI=10.1073/pnas.77.10.5938
Pickering L.A., Kronenberg L.H., Stewart W.E. II
Spontaneous production of human interferon.
Proc. Natl. Acad. Sci. U.S.A. 77:5938-5942(1980)

PubMed=6193516; DOI=10.1073/pnas.80.17.5397
Williamson B.D., Carswell E.A., Rubin B.Y., Prendergast J.S., Old L.J.
Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.
Proc. Natl. Acad. Sci. U.S.A. 80:5397-5401(1983)

PubMed=3863119; DOI=10.1073/pnas.82.19.6637
Rubin B.Y., Anderson S.L., Sullivan S.A., Williamson B.D., Carswell E.A., Old L.J.
Purification and characterization of a human tumor necrosis factor from the LuKII cell line.
Proc. Natl. Acad. Sci. U.S.A. 82:6637-6641(1985)

Encyclopedic resources Wikidata; Q54903260
Entry history
Entry creation15-Nov-2017
Last entry update29-Jun-2023
Version number6