Cellosaurus cell line BEAS-2B/c-raf-1 (CVCL

Cross-references
Cell line name	BEAS-2B/c-raf-1
Synonyms	BEAS 2B-c-raf-1; 2B-raf
Accession	CVCL_LJ65
Resource Identification Initiative	To cite this cell line use: BEAS-2B/c-raf-1 (RRID:CVCL_LJ65)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9864. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:9829; RAF1. Transformant: Ad12-SV40 hybrid virus. Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0168 (BEAS-2B)
Sex of cell	Male
Category	Transformed cell line
Publications	PubMed=1712250 Pfeifer A.M.A., Jones R.T., Bowden P.E., Mann D.L., Spillare E.A., Klein-Szanto A.J.P., Trump B.F., Harris C.C. Human bronchial epithelial cells transformed by the c-raf-1 and c-myc protooncogenes induce multidifferentiated carcinomas in nude mice: a model for lung carcinogenesis. Cancer Res. 51:3793-3801(1991) Patent=US5443954 Reddel R.R., Yang K., Rhim J.S., Brash D.E., Su R.T., Lechner J.F., Gerwin B.I., Harris C.C., Amstad P.A. Immortalized non-tumorigenic human bronchial epithelial cell lines. Patent number US5443954, 22-Aug-1995
Encyclopedic resources	Wikidata; Q54795948
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	11