ID   HB1.F3.EGFRviii
AC   CVCL_LJ46
SY   F3.EGFRviii
DR   Wikidata; Q54881354
RX   PubMed=28830458;
CC   Characteristics: EGFRviii expression is doxycycline inducible (PubMed=28830458).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: v-Myc.
CC   Derived from site: In situ; Fetal brain, telencephalon; UBERON=UBERON_0014371.
CC   Cell type: Neural stem cell; CL=CL_0000047.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_LJ44 ! HB1.F3
SX   Female
AG   14FW
CA   Transformed cell line
DT   Created: 15-11-17; Last updated: 19-12-24; Version: 9
//
RX   PubMed=28830458; DOI=10.1186/s12943-017-0703-y; PMCID=PMC5567886;
RA   Kwon S.-J., Kwon O.-S., Kim K.-T., Go Y.-H., Yu S.-I., Lee B.-H.,
RA   Miyoshi H., Oh E., Cho S.-J., Cha H.-J.;
RT   "Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in
RT   cancerous neural stem cells, expressing EGFRviii.";
RL   Mol. Cancer 16:140.1-140.13(2017).
//