Cellosaurus cell line EU-11 (CVCL

Cross-references
Cell line name	EU-11
Synonyms	Emory University-11
Accession	CVCL_LI25
Resource Identification Initiative	To cite this cell line use: EU-11 (RRID:CVCL_LI25)
Comments	Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=9823951).
Disease	Childhood B acute lymphoblastic leukemia (NCIt: C9140) Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	1Y
Category	Cancer cell line
Publications	PubMed=7630190 Zhou M.-X., Gu L.-B., James C.D., He J., Yeager A.M., Smith S.D., Findley H.W. Jr. Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 9:1159-1161(1995) PubMed=9823951; DOI=10.1038/sj.leu.2401198 Zhou M.-X., Gu L.-B., Yeager A.M., Findley H.W. Jr. Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia 12:1756-1763(1998)
Cell line databases/resources	cancercelllines; CVCL_LI25
Encyclopedic resources	Wikidata; Q54832859
Polymorphism and mutation databases	IARC_TP53; 10048
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	11