Cell line name |
KT [Human leukemia] |
Accession |
CVCL_LI23 |
Resource Identification Initiative |
To cite this cell line use: KT [Human leukemia] (RRID:CVCL_LI23) |
Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Sex unspecified |
Age at sampling |
Children |
Category |
Cancer cell line |
Publications | PubMed=7630190 Zhou M.-X., Gu L.-B., James C.D., He J., Yeager A.M., Smith S.D., Findley H.W. Jr. Homozygous deletions of the CDKN2 (MTS1/p16ink4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 9:1159-1161(1995) PubMed=7888679; DOI=10.1182/blood.V85.6.1608.bloodjournal8561608 Zhou M.-X., Yeager A.M., Smith S.D., Findley H.W. Jr. Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene. Blood 85:1608-1614(1995) PubMed=9108419; DOI=10.1182/blood.V89.8.2986 Findley H.W. Jr., Gu L.-B., Yeager A.M., Zhou M.-X. Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. Blood 89:2986-2993(1997) PubMed=9823951; DOI=10.1038/sj.leu.2401198 Zhou M.-X., Gu L.-B., Yeager A.M., Findley H.W. Jr. Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression. Leukemia 12:1756-1763(1998) |
Cross-references |
Encyclopedic resources |
Wikidata; Q54900515
|
Entry history |
Entry creation | 15-Nov-2017 |
Last entry update | 21-Mar-2023 |
Version number | 6 |
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