ID   HATL
AC   CVCL_LI16
DR   Wikidata; Q54881331
RX   PubMed=8486778;
RX   PubMed=10637496;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175Pro (c.524G>C); Zygosity=Heterozygous (PubMed=8486778).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_LI15 ! HABL
SX   Female
AG   10Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 19-12-24; Version: 9
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RX   PubMed=8486778; DOI=10.1172/JCI116435; PMCID=PMC288211;
RA   Yeargin J., Cheng J., Yu A.L.-T., Gjerset R.A., Bogart M., Haas M.;
RT   "p53 mutation in acute T cell lymphoblastic leukemia is of somatic
RT   origin and is stable during establishment of T cell acute
RT   lymphoblastic leukemia cell lines.";
RL   J. Clin. Invest. 91:2111-2117(1993).
//
RX   PubMed=10637496; DOI=10.1038/sj.leu.2401604;
RA   Drexler H.G., Fombonne S., Matsuo Y., Hu Z.-B., Hamaguchi H.,
RA   Uphoff C.C.;
RT   "p53 alterations in human leukemia-lymphoma cell lines: in
RT   vitro artifact or prerequisite for cell immortalization?";
RL   Leukemia 14:198-206(2000).
//